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COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss.

Janneke A C van BaarElena B KostovaJohn AlloteyShakila ThangaratinamJavier R ZamoraMercedes BonetCaron Rahn KimLynne M MofensonHeinke KunstAsma KhalilElisabeth van LeeuwenJulia KeijzerMarije StrikwerdaBethany ClarkMaxime VerschuurenArri CoomarasamyMariëtte GoddijnMadelon van Welynull null
Published in: Human reproduction update (2023)
Our study found no indication that SARS-CoV-2 infection in the first or second trimester increases the risk of miscarriages. To provide better risk estimates, well-designed studies are needed that include pregnant women with and without SARS-CoV-2 infection at conception and early pregnancy and consider the association of clinical manifestation and severity of SARS-CoV-2 infection with pregnancy loss, as well as potential confounding factors such as previous pregnancy loss. For clinical practice, pregnant women should still be advised to take precautions to avoid risk of SARS-CoV-2 exposure and receive SARS-CoV-2 vaccination.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • pregnant women
  • pregnancy outcomes
  • preterm birth
  • coronavirus disease
  • clinical practice
  • risk factors
  • risk assessment
  • human health