Pathogen surveillance in the informal settlement, Kibera, Kenya, using a metagenomics approach.
Rene S HendriksenOksana LukjancenkoPatrick MunkMathis H HjelmsøJennifer R VeraniEric Ng'enoGodfrey BigogoSamuel KiplangatTraoré OumarLasse BergmarkTimo RöderJohn C NeatherlinOnyango ClaytonTine HaldSusanne KarlsmoseSünje J PampBarry FieldsJoel M MontgomeryFrank M AarestrupPublished in: PloS one (2019)
The metagenomic surveillance approach for monitoring circulating pathogens in sewage was able to detect putative pathogen and resistance loads in an urban informal settlement. Thus, valuable if generated in real time to serve as a comprehensive infectious disease agent surveillance system with the potential to guide disease prevention and treatment. The approach may lead to a paradigm shift in conducting real-time global genomics-based surveillance in settings with limited access to health care.