Isohemagglutinin titering performed on an automated solid-phase and hemagglutinin-based analyzer is comparable to results obtained by manual gel testing.

Kimberly LallyRobert L KruseHeather SmetanaRivcah DavisAngela RootsChristi MarshallPaul M NessAmy E DeZernDouglas E GladstoneDaniel C BrennanNiraj M DesaiAaron A R Tobian Evan M Bloch Eric Abraham Gehrie

Published in: Transfusion (2020)

Manual and automated methodologies yielded similar isohemagglutinin titers. Separate quantification of IgM and IgG isohemagglutinins via automated titration may yield additional insight into hemolysis, graft survival after ABO-incompatible transplantation, and red blood cell engraftment after ABO-incompatible stem cell transplant.

Keyphrases

red blood cell
stem cells
deep learning
machine learning
high throughput
cell therapy
bone marrow
single cell
mesenchymal stem cells