Preclinical imaging of epidermal growth factor receptor with ABY-029 in soft-tissue sarcoma for fluorescence-guided surgery and tumor detection.
Kimberley S SamkoeHira S SardarBrent D BatesNiki N TselepidakisJason R GunnKevin A Hoffer-HawlikJoachim FeldwischBrian W PogueKeith D PaulsenEric R HendersonPublished in: Journal of surgical oncology (2019)
ABY-029 demonstrates promise to assist in wide local excision of soft-tissue sarcomas. Further clinical evaluation of in situ or freshly excised ex vivo tissues using fluorescence imaging systems is warranted.
Keyphrases
- fluorescence imaging
- epidermal growth factor receptor
- soft tissue
- photodynamic therapy
- tyrosine kinase
- advanced non small cell lung cancer
- minimally invasive
- coronary artery bypass
- gene expression
- high resolution
- high grade
- big data
- single molecule
- loop mediated isothermal amplification
- real time pcr
- label free
- surgical site infection
- deep learning
- percutaneous coronary intervention
- machine learning
- acute coronary syndrome
- mesenchymal stem cells
- mass spectrometry
- sensitive detection