Osteoporosis in men with hypogonadism because of ApoA-I Leu75Pro amyloidosis under long-term testosterone therapy.
Paolo FacondoAndrea DelbarbaLetizia Chiara PezzaioliAlberto FerlinCarlo CappelliPublished in: Andrology (2023)
Men with hypogonadism because of Apo A-I Leu75Pro amyloidosis under long-term TRT had a high burden of low bone mass (64%) and VFs (almost 15%). Osteopenia-osteoporosis was more frequently observed in older patients with multi-organ disease, which might contribute to impair bone health beyond hypogonadism.
Keyphrases
- bone mineral density
- replacement therapy
- postmenopausal women
- middle aged
- body composition
- smoking cessation
- anti inflammatory
- healthcare
- public health
- multiple myeloma
- soft tissue
- mental health
- physical activity
- bone loss
- stem cells
- bone regeneration
- community dwelling
- health promotion
- mesenchymal stem cells
- cell therapy