A Short-Term Western Diet Impairs Cholesterol Homeostasis and Key Players of Beta Amyloid Metabolism in Brain of Middle Aged Rats.

Maria Stefania SpagnuoloValentina PallottiniArianna MazzoliLucia IannottaClaudia ToniniBarbara MoroneMarcus StåhlmanRaffaella CrescenzoMaria StrazzulloSusanna IossaLuisa Cigliano

Published in: Molecular nutrition & food research (2020)

Overall these data show that a western diet is associated with perturbation of cholesterol homeostasis in middle aged rats, mostly in hippocampus. This might trigger molecular events involved in the onset of neurodegenerative diseases.

Keyphrases

middle aged
weight loss
physical activity
south africa
low density lipoprotein
cerebral ischemia
electronic health record
white matter
big data
cognitive impairment
multiple sclerosis
brain injury
high school