Effects of hydroxyurea on fertility in male and female sickle cell disease patients. A systemic review and meta-analysis.

Sarah SewaralthahabLujain A AlsubkiMaram S AlhrabiAbdulrahman Alsultan

Published in: PloS one (2024)

This systemic review and meta-analysis suggest that the use of HU for SCD impacts seminal fluid parameters in males and can diminish AMH levels and ovarian reserves in females.

Keyphrases

sickle cell disease
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
peritoneal dialysis
patient reported