Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats.

Sevil Korkmaz-IcözBartosz SzczesnyMichela MarcattiShiliang LiMihály RuppertFelix LasitschkaSivakkanan LoganathanCsaba SzabóGábor Szabó

Published in: British journal of pharmacology (2017)

This article is part of a themed section on Inventing New Therapies Without Reinventing the Wheel: The Power of Drug Repurposing. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.2/issuetoc.

Keyphrases

oxidative stress
dna damage
benign prostatic hyperplasia
lower urinary tract symptoms
diabetic rats
induced apoptosis
endothelial cells
signaling pathway
heat shock protein