Immunomodulators after the discontinuation of anti-tumor necrosis factor-alpha antibody treatment and relapse in ulcerative colitis: A multicenter cohort study.
Kunio AsonumaKeiji OzekiHajime YamazakiShinji OkabayashiSoh OkanoRyo OzakiNobuaki NishimataHiroki KiyoharaNaoki IchinariTaku KobayashiMasahiro YamadaMao MatsubayashiYoko YokoyamaShoko ArimitsuJunji UmenoYoshinori MunetomoKatsuyoshi AndoShinichiro Shinzakinull nullPublished in: Journal of gastroenterology and hepatology (2023)
Immunomodulators were not associated with relapse after discontinuing anti-TNF-α antibody treatment in patients with UC. Careful patient follow-up is needed when discontinuing due to side effects or when the patient is of a younger age at the time of discontinuation.