Effect of cartilaginous endplates on extruded disc resorption in lumbar disc herniation.
Kenichi KawaguchiKatsumi HarimayaYoshihiro MatsumotoMitsumasa HayashidaSeiji OkadaKeiichiro IidaGo KatoKuniyoshi TsuchiyaToshio DoiYoshinao OdaYukihide IwamotoYasuharu NakashimaPublished in: PloS one (2018)
There is an association between LDH with endplate degeneration and cartilaginous herniation, with Modic type 2 predominating. Furthermore, neovascularization and macrophage infiltration, especially if the amount of cartilage is high, are likely to be less frequent in cartilaginous herniation, leading to failure in the spontaneous remission of clinical symptoms.