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A novel p.Gly417Valfs*12 mutation in the MTTP gene causing abetalipoproteinemia: Presentation of the first patient in Mexico and analysis of the previously reported cases.

Perla Graciela Rodríguez GutiérrezJuan Ramón González GarcíaYolanda Alicia Castillo De LeónJuan Rafael Zárate GuerreroMaría Teresa Magaña-Torres
Published in: Journal of clinical laboratory analysis (2020)
The first Mexican patient with abetalipoproteinemia presents a novel MTTP mutation p.Gly417Valfs*12. Three factors that could modulate the phenotype in abetalipoproteinemia were identified: age at diagnosis, treatment, and the causal mutation.
Keyphrases
  • case report
  • genome wide
  • copy number
  • dna methylation
  • transcription factor
  • smoking cessation