Tight junction, mucin, and inflammasome-related molecules are differentially expressed in eosinophilic, mixed, and neutrophilic experimental asthma in mice.

Hern-Tze Tina TanStefanie HagnerFiorella RuchtiUrszula RadzikowskaGe TanCan AltunbulakliAndrzej EljaszewiczMarcin MoniuszkoMübeccel AkdişCezmi A AkdisHolger GarnMilena Sokolowska

Published in: Allergy (2018)

Our findings suggest that differential expression of TJ, mucin, and inflammasome-related molecules in distinct inflammatory phenotypes of asthma may be linked to pathophysiology and might reflect the differences observed in the clinic.

Keyphrases

chronic obstructive pulmonary disease
lung function
primary care
allergic rhinitis
blood brain barrier
oxidative stress
metabolic syndrome
high fat diet induced
skeletal muscle
air pollution
insulin resistance