High sensitivity and specificity of a 5-analyte protein and microRNA biosignature for identification of active tuberculosis.

Jessica L PedersenSimone E BarryNilesh J BokilMagda EllisYuRong YangGuangyu GuanXiaolin WangAlen FaizWarwick J BrittonBernadette M Saunders

Published in: Clinical & translational immunology (2021)

A novel combination of miRNA and proteins significantly improves the sensitivity and specificity as a biosignature over single biomarker candidates and may be useful for the development of a non-sputum test to aid the diagnosis of active TB disease.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
structural basis
hiv aids
protein protein
emergency department
binding protein
human immunodeficiency virus
adverse drug
antiretroviral therapy
hiv infected