Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection.
Valentine Faure BardonGilles PeytavinMinh Patrick LêTiffany GuilleminotElisabeth ElefantJulien StirnemannMarianne Leruez-VilleYves VillePublished in: PloS one (2020)
Drugs' concentrations in the fetal side should be in the range for in utero treatment of fetuses infected with CMV as the mean FC was superior to the EC50 for both molecules.