CD163+ cytokine-producing cDC2 stimulate intratumoral type 1 T cell responses in HPV16-induced oropharyngeal cancer.

Saskia J A M SantegoetsChantal L DuurlandEkaterina J JordanovaVanessa J van HamIlina EhsanNikki M LoofVipin NarangCharles A DutertreFlorent GinhouxSylvia L van EgmondMarij J P WeltersSjoerd H Van der Burg

Published in: Journal for immunotherapy of cancer (2021)

These data suggest an important role for intratumoral CD163+ cDC2 in stimulating tumor-infiltrating T cells to exert their antitumor effects.

Keyphrases

cell cycle
papillary thyroid
high glucose
nk cells
electronic health record
squamous cell
diabetic rats
big data
drug induced
endothelial cells
deep learning
lymph node metastasis