Clinical spectrum and outcome of children with deficiency of adenosine deaminase 2 (DADA2): multicentric experience from India.
Sathish KumarAkagri ChughSamantha Cheryl KumarAnu PunnenChandrika BhatPratap PatraVijay ViswanathanAditya GuptaMukul AggarwalAmiya Ranjan NayakLokesh LingappaJyoti SharmaNeerja GuptaPriyanka NaranjeManisha JanaNarendra Kumar BagriPankaj HariAthimalaipet V RamananPublished in: Rheumatology (Oxford, England) (2024)
DADA-2 closely resembles PAN; early age of onset and CNS stroke are striking differentiating features from classic PAN. Most children respond well to anti-TNF agents without serious adverse events during short-term follow-up.