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Discovery of endogenous nitroxyl as a new redox player in Arabidopsis thaliana.

Magdalena Arasimowicz-JelonekJ Floryszak-WieczorekSebastián Ángel SuarezFabio DoctorovichE Sobieszczuk-NowickaS Bruce KingG MilczarekT RębiśJ GajewskaPrzemysław JagodzikM Żywicki
Published in: Nature plants (2022)
Nitroxyl (HNO) is the one-electron reduced and protonated congener of nitric oxide (•NO), owning a distinct chemical profile. Based on real-time detection, we demonstrate that HNO is endogenously formed in Arabidopsis. Senescence and hypoxia induce shifts in the redox balance, triggering HNO decay or formation mediated by non-enzymatic •NO/HNO interconversion with cellular reductants. The stimuli-dependent HNO generation supports or competes with •NO signalling, depending on the local redox environment.
Keyphrases
  • arabidopsis thaliana
  • nitric oxide
  • endothelial cells
  • hydrogen peroxide
  • electron transfer
  • dna damage
  • nitric oxide synthase
  • label free
  • single cell
  • cell wall
  • plant growth