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Development and Evaluation of MR-Based Radiogenomic Models to Differentiate Atypical Lipomatous Tumors from Lipomas.

Sarah C ForemanOscar Llorián-SalvadorDiana E DavidVerena K N RösnerJon F RischewskiGeorg C FeuerriegelDaniel W KrampIna LuikenAnn-Kathrin LohseJurij KieferCarolin MoglerCarolin KnebelMatthias JungMiguel A Andrade-NavarroBurkhard RostStephanie E CombsMarcus R MakowskiKlaus WoertlerJan C PeekenAlexandra S Gersing
Published in: Cancers (2023)
A radiogenomic model combining features from multiple MR sequences showed the best performance in predicting the MDM2 gene amplification status. The model showed a higher accuracy compared to the radiology residents, though lower compared to the attending radiologist.
Keyphrases
  • magnetic resonance
  • contrast enhanced
  • gene expression
  • copy number
  • transcription factor
  • computed tomography
  • dna methylation