Drug perturbation gene set enrichment analysis (dpGSEA): a new transcriptomic drug screening approach.

Mike FangBrian RichardsonCheryl M CameronJean-Eudes DazardMark J Cameron

Published in: BMC bioinformatics (2021)

dpGSEA is an approach that uniquely enriches on drug-defined gene sets while considering directionality of gene modulation. We recommend dpGSEA as an exploratory tool to screen for possible drug targeting molecules.

Keyphrases

copy number
genome wide
adverse drug
genome wide identification
gene expression
high throughput
emergency department
dna methylation
single cell
genome wide analysis