A meta-analysis of the best available evidence (level 2a) demonstrates that donor obesity does not seem to have a negative impact on graft or patient outcomes. The available studies might be subject to selection bias as the grafts from obese donors are usually subject to biopsy to exclude steatosis and the recipients usually belong to the low-risk group. Future research is needed to evaluate the impact of donors subgrouped by various higher BMI on graft and patient-related outcomes as well as to capture data of the discarded grafts from obese donors; hence, selection criteria for the grafts that could be used for transplantation from obese donors is identified.
Keyphrases
- weight loss
- metabolic syndrome
- insulin resistance
- kidney transplantation
- adipose tissue
- type diabetes
- bariatric surgery
- weight gain
- high fat diet induced
- obese patients
- high fat diet
- body mass index
- glycemic control
- case report
- electronic health record
- ultrasound guided
- cell therapy
- mesenchymal stem cells
- drug induced
- data analysis
- case control