Synthesis and Optical Properties of Thiazolo-Chlorin and Porphyrin Skeletons.
Takeo NakanoHiroaki ImotoKensuke NakaPublished in: Organic letters (2021)
Macrocyclic π-skeletons containing a thiazole moiety were synthesized via MacDonald [3 + 1]-type condensation. The construction of thiazolochlorin 1a and thiazoloporphyrin 1b depended on the conformation of the thiazole moieties, and their 18π-systems expanded along the molecular y and x axes, respectively. In particular, the structure of thiazolochlorin 1a was studied in detail using 2D nuclear magnetic resonance methods. The optical properties in solution were measured and discussed based on both experimental data and computational studies.
Keyphrases
- oxide nanoparticles
- photodynamic therapy
- magnetic resonance
- solid state
- electronic health record
- case control
- molecular dynamics simulations
- big data
- contrast enhanced
- metal organic framework
- single molecule
- computed tomography
- energy transfer
- machine learning
- data analysis
- electron transfer
- artificial intelligence