Dynamic thiol/disulphide homeostasis and pathogenesis of Kawasaki disease.

Ayşe Kaman Türkan Aydın TekeZeynep Gökçe Gayretli AydınGülin Karacan KüçükaliSalim NeşelioğluÖzcan ErelGönül Tanır

Published in: Pediatrics international : official journal of the Japan Pediatric Society (2020)

The KD patients had lower plasma thiol (native and total) and higher disulphide thiol than controls, indicating that dynamic thiol/disulphide homeostasis might be an important indicator of inflammation in KD. Alteration and shifting of thiol/disulphide homeostasis to the oxidized side are correlated with the pathogenesis of KD and CAL.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
oxidative stress
prognostic factors
patient reported outcomes
low density lipoprotein