Oestrogen inhibits salt-dependent hypertension by suppressing GABAergic excitation in magnocellular AVP neurons.
Xiangyan JinWoong Bin KimMi-Na KimWon Woo JungHyung Kyung KangEun-Hwa HongYoon Sik KimWan Joo ShimHee Chul HanChristopher Scott ColwellYoung-Beom KimYang In KimPublished in: Cardiovascular research (2022)
Based on these results, we conclude that E2 inhibits salt-dependent hypertension by suppressing GABAergic excitation to decrease the hormonal output of AVP neurons.