Echinomycin did not affect the safety of fracture healing: an experimental pilot study on a murine femur fracture model.
Thorsten JentzschStefan M ZimmermannFlora NichollsPaolo CinelliHans-Peter SimmenClément M L WernerPublished in: Patient safety in surgery (2016)
As a novel finding, echinomycin did not inhibit fracture healing or callus formation in this in vivo murine standard femur fracture model pilot study. Further studies involving a larger number of cases, quantitative assessment with CT scans and histopathological analysis are needed before generalizing the results of this pilot study.