Impact of blood collection and processing on peripheral blood gene expression profiling in type 1 diabetes.
Linda YipRebecca FuhlbriggeMark A AtkinsonC Garrison FathmanPublished in: BMC genomics (2017)
We showed that the gene expression profile of samples processed using the Tempus system is more accurate than that of samples processed using the PAXgene system. Variation in sample processing can result in misleading changes in gene expression. However, these differences can be minimized by measuring gene expression directly in whole blood lysates.