FTY720 Suppresses Liver Tumor Growth and Metastasis by Reducing Circulating Regulating T Cells and Enhancing the Anti-Tumor Effect of Rapamycin.

Chang Xian LiXin Xiang YangHong Wei WangXiang Cheng LiKevin Tak Pan NgChung Mau LoChang Xian Li

Published in: OncoTargets and therapy (2020)

FTY720 suppressed liver tumor growth and metastasis by reducing the population of circulating Tregs and enhancing the anti-tumor effect of rapamycin. It was suggested that FTY720 single or combined with rapamycin might provide novel insight for suppressing tumor growth and metastasis for HCC patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
signaling pathway
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes