Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia.
Emma Louise van der EndeMeifang XiaoDesheng XuJackie M PoosJessica L PanmanLize C JiskootLieke H MeeterElise Gp DopperJanne M PapmaCarolin HellerRhian S ConveryKatrina MooreMartina BocchettaMollie NeasonGeorgia PeakmanDavid M CashCharlotte E TeunissenCaroline GraffMatthis SynofzikFermin MorenoElizabeth C FingerRaquel Sánchez-ValleRik VandenbergheRobert LaforceMario MasellisMaria Carmela TartagliaJames Benedict RoweChristopher R ButlerSimon DucharmeAlex GerhardAdrian DanekJohannes LevinYolande Al PijnenburgMarkus OttoBarbara BorroniFabrizio TagliaviniAlexandre de MendoncaIsabel SantanaDaniela GalimbertiHarro SeelaarJonathan D RohrerPaul F WorleyJohn Cornelis van Swietennull nullPublished in: Journal of neurology, neurosurgery, and psychiatry (2020)
We conclude that NPTX2 is a promising synapse-derived disease progression biomarker in genetic FTD.