An optimization and refinement of the whole-gut transit assay in mice.

Simone L Schonkeren Saskia Seeldrayers Meike S Thijssen Werend Boesmans Ramon C J Langen Veerle Melotte

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2023)

This refined whole-gut transit assay provides a reliable approach to measure whole-gut transit time in mice in a more physiological context, with reduced variability compared to the standard method.

Keyphrases

high fat diet induced
high throughput
type diabetes
metabolic syndrome
wild type
skeletal muscle
adipose tissue