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The PNPLA3 rs738409 C>G variant influences the association between low skeletal muscle mass and NAFLD: the Shanghai Changfeng Study.

Ming-Feng XiaLing-Yan ChenLi WuHui MaQian LiQiqige AletengYu HuWan-Yuan HeJian GaoHuan-Dong LinXin Gao
Published in: Alimentary pharmacology & therapeutics (2019)
Low ASM% is associated with NAFLD and liver fibrosis. Dissociation of sarcopenia and NAFLD was found in PNPLA3 GG genotype carriers. A stratification based on PNPLA3 genotypes might facilitate personalised treatment for NAFLD.
Keyphrases
  • liver fibrosis
  • skeletal muscle
  • combination therapy