Serum aryl hydrocarbon receptor activity is associated with survival in patients with alcohol-associated hepatitis.
Tomoo YamazakiTetsuya KounoCynthia Li-Shin HsuPhillipp HartmannSusan MayoXinlian ZhangPeter StärkelFrancisco Bosques-PadillaElizabeth C VernaJuan G AbraldesRobert S BrownVictor VargasJose AltamiranoJuan CaballeríaDebbie L ShawcrossAlexandre LouvetMichael R LuceyPhilippe MathurinGuadalupe Garcia-TsaoRamon BatallerBernd Schnablnull nullPublished in: Hepatology (Baltimore, Md.) (2024)
Serum AhR activity was significantly higher in patients with AH compared with controls and individuals with AUD, and this increased activity was associated with higher mortality. Consequently, serum AhR activity holds potential as a prognostic marker.