Effect of Gender on Lung Function and Patient-Reported Outcomes in Patients with COPD Receiving Nebulized Glycopyrrolate.
Jill A OharAyca Ozol-GodfreyThomas GoodinShahin SanjarPublished in: International journal of chronic obstructive pulmonary disease (2020)
Treatment with nebulized GLY resulted in lung function, SGRQ total score, and EXACT-RS total score improvements regardless of gender. However, only EXACT-RS showed significantly greater improvements in women compared with men. Treatment with GLY was generally well tolerated across genders. These data support the efficacy and safety of GLY 25 µg BID in patients with moderate-to-very-severe COPD, independent of gender. Gender similarities in airflow improvement and differences in symptom-reporting augment the evidence supporting the consideration of individualized treatment plans for COPD patients.
Keyphrases
- lung function
- chronic obstructive pulmonary disease
- cystic fibrosis
- patient reported outcomes
- air pollution
- mental health
- end stage renal disease
- ejection fraction
- type diabetes
- peritoneal dialysis
- pregnant women
- chronic kidney disease
- metabolic syndrome
- combination therapy
- deep learning
- health insurance
- drug induced