Serum biomarkers associated with radiographic skeletal maturity indicators: A systematic review and meta-analysis.
Tulika TripathiGayatri GaneshNavneet SinghPriyank RaiPublished in: Journal of orthodontics (2022)
Among the various biomarkers evaluated, serum IGF-1 was the most associated with different stages of radiographic skeletal maturity indicators with its levels peaking at CS3 in women and CS4 in men.