Discovery and validation of methylation signatures in blood-based circulating tumor cell-free DNA in early detection of colorectal carcinoma: a case-control study.
Jinke SuiXianrui WuChenyang WangGuoqiang WangChengcheng LiJing ZhaoYuzi ZhangJianxing XiangYu XuWeiqi NianFuao CaoGuanyu YuZheng LouLiqiang HaoLianjie LiuBingsi LiZhihong ZhangShangli CaiHao LiuPing LanWeiyuan ZhangPublished in: Clinical epigenetics (2021)
Together our findings showed that ctDNA methylation markers were promising in the early detection of CRC. Further validation of this model is warranted in prospective studies.