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Langerhans cells mediate the skin-induced tolerance to ovalbumin via Langerin in a murine model.

Yang LuoSu WangXiaochun LiuHe WenWei LiXu Yao
Published in: Allergy (2019)
Our data suggested that LCs were critical in the intact skin-induced tolerance to protein antigen via Langerin, and LCs might be targeted via Langerin to regulate the immune responses in systemic and (or) skin inflammatory diseases.
Keyphrases
  • immune response
  • soft tissue
  • high glucose
  • diabetic rats
  • wound healing
  • oxidative stress
  • induced apoptosis
  • drug induced
  • cell cycle arrest
  • big data
  • cell death
  • dendritic cells
  • cancer therapy
  • toll like receptor