Estimated Doses to the Heart, Lungs and Oesophagus and Risks From Typical UK Radiotherapy for Early Breast Cancer During 2015-2023.
F HoltA IvanovaZ WangS DarbyF DuaneG NtentasS OliverosB LaveryK ShahA EichholzD DodwellC TaylorPublished in: Clinical oncology (Royal College of Radiologists (Great Britain)) (2024)
The typical doses to these organs may be combined with dose-response relationships to estimate radiation risks. Estimated 30-year absolute lung cancer mortality risks from modern UK breast cancer radiotherapy for patients irradiated when aged 50 years were 2-6% for long-term continuing smokers, and <1% for non-smokers. Estimated 30-year mortality risks for heart disease were <1%.
Keyphrases
- human health
- end stage renal disease
- early stage
- early breast cancer
- cardiovascular events
- smoking cessation
- radiation induced
- risk assessment
- ejection fraction
- locally advanced
- newly diagnosed
- radiation therapy
- chronic kidney disease
- heart failure
- peritoneal dialysis
- pulmonary hypertension
- squamous cell carcinoma
- cardiovascular disease
- atrial fibrillation
- rectal cancer