Effects of Elexacaftor/Tezacaftor/Ivacaftor on Cardiorespiratory Polygraphy Parameters and Respiratory Muscle Strength in Cystic Fibrosis Patients with Severe Lung Disease.

Alessandro GiallongoGiuseppe Fabio ParisiMaria PapaleSara MantiEnza MuléDonatella AloisioVito TerlizziNovella RotoloSalvatore Leonardi

Published in: Genes (2023)

We provide further evidence on the efficacy of the CFTR modulators ELX/TEZ/IVA, adding information about their effect on the respiratory muscles' performance and cardiorespiratory polygraphy parameters in CF patients with severe lung disease.

Keyphrases

cystic fibrosis
pseudomonas aeruginosa
lung function
body composition
early onset
high intensity
small molecule
respiratory tract
drug induced