PNPLA3 rs738409 is associated with renal glomerular and tubular injury in NAFLD patients with persistently normal ALT levels.
Dan-Qin SunKenneth I ZhengGang XuHong-Lei MaHao-Yang ZhangXiao-Yan PanPei-Wu ZhuXiao-Dong WangGiovanni TargherChristopher D ByrneYong-Ping ChenWei-Jie YuanMing-Hua ZhengPublished in: Liver international : official journal of the International Association for the Study of the Liver (2019)
Patients with NAFLD and persistently nALT, who carry the PNPLA3 rs738409 G allele, are at higher risk of early glomerular and tubular damage. We suggest PNPLA3 genotyping may help identify patients with NAFLD at higher risk of RTI.