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Acacetin enhances the therapeutic efficacy of doxorubicin in non-small-cell lung carcinoma cells.

Reenu PuniaKomal RainaRajesh AgarwalRana P Singh
Published in: PloS one (2017)
These findings suggested that acacetin augments the cytotoxicity of doxorubicin at lower concentrations in lung cancer cells. Their combination leads to more retention of doxorubicin in the cells by modulating drug trasporter and thus enhances its therapeutic potential.
Keyphrases
  • drug delivery
  • cancer therapy
  • induced apoptosis
  • cell cycle arrest
  • signaling pathway
  • single cell
  • cell therapy
  • stem cells
  • cell death
  • oxidative stress
  • emergency department
  • cell proliferation