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Synthesis, In Silico Log p Study, and In Vitro Analgesic Activity of Analogs of Tetrapeptide FELL.

Boryana BorisovaHristina NochevaStéphane GérardMarie Laronze-CochardStefan DobrevSilvia E AngelovaStoyko PetrinDancho L Danalev
Published in: Pharmaceuticals (Basel, Switzerland) (2023)
The best analgesic activity is found in the parent compound FELL and its C-terminal amide analog.
Keyphrases
  • molecular docking
  • neuropathic pain
  • anti inflammatory
  • molecular dynamics simulations