A Novel Schizophrenia Diagnostic Model Based on Statistically Significant Changes in Gene Methylation in Specific Brain Regions.

Dong-Hua ZouYufen QiuRongjie LiYoushi MengYuan Wu

Published in: BioMed research international (2020)

DNA methylation patterns in SCZ vary across different brain regions, which may be a useful epigenetic characteristic for diagnosing SCZ. Our novel model based on SCZ-gene methylation shows promising diagnostic power.

Keyphrases

dna methylation
genome wide
copy number
gene expression
white matter
resting state
bipolar disorder
cerebral ischemia
functional connectivity
blood brain barrier