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CXCR4, CXCR5 and CD44 May Be Involved in Homing of Lymphoma Cells into the Eye in a Patient Derived Xenograft Homing Mouse Model for Primary Vitreoretinal Lymphoma.

Neele BabstLisa K IsbellFelix RommelAysegul TuraMahdy RanjbarSalvatore GrisantiCordula TschuchJulia SchuelerSoroush DoostkamPeter C ReinacherJustus DuysterVinodh KakkasseryNikolas von Bubnoff
Published in: International journal of molecular sciences (2022)
CD20+ PCNSL lymphoma cells infiltrating the eye co-express distinct homing receptors such as CXCR4 and CXCR5 in a PVRL homing mouse model. These receptors may be involved in PVRL homing into the eye.
Keyphrases
  • mouse model
  • induced apoptosis
  • diffuse large b cell lymphoma
  • cell cycle arrest
  • cell migration
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • signaling pathway
  • cell proliferation