Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats.

Gregory R KeeleJeremy W ProkopHong HeKatie HollJohn LittrellAaron DealSanja FrancicLeilei CuiDaniel M GattiKarl W BromanMichael TschannenShirng-Wern TsaihMaie ZagloulYunjung KimBrittany BaurJoseph FoxMelanie RobinsonShawn LevyMichael J FlisterRichard MottWilliam Valdar Leah C Solberg Woods

Published in: Obesity (Silver Spring, Md.) (2017)

These data demonstrate the power of HS rats for identification of known and novel heritable mediators of obesity traits.

Keyphrases

genome wide
insulin resistance
copy number
weight gain
metabolic syndrome
type diabetes
bioinformatics analysis
weight loss
high resolution
air pollution
dna methylation
high fat diet induced
adipose tissue
big data
physical activity