Login / Signup

Development and validation of broad-spectrum magnetic particle labelling processes for cell therapy manufacturing.

Richard HarrisonHilda Anaid Lugo LeijaStephanie StrohbueckerJames CrutchleySarah MarshChris DenningAlicia El HajVirginie Sottile
Published in: Stem cell research & therapy (2018)
Our results show that a generic MP labelling strategy was successfully developed for a range of clinically relevant cell populations, in both monolayer and suspension cultures. MP-labelled cell populations were able to undergo transient low-temperature storage whilst maintaining functional capacity in vitro. These results suggest that this MP labelling approach can be integrated into cell manufacturing and cold chain transport processes required for future cell therapy approaches.
Keyphrases
  • cell therapy
  • stem cells
  • mesenchymal stem cells
  • single cell
  • bone marrow
  • cerebral ischemia
  • transition metal