Dexmedetomidine's Effects on the Livers and Kidneys of Rats with Pancreatic Ischemia-Reperfusion Injury.
Hasan BostancıSelin ErelAysegül KucukGülay KipSaban Cem SezenSeda GokgozMuharrem AtlıFeyza AktepeKursat DikmenMustafa ArslanMustafa KavutçuPublished in: Drug design, development and therapy (2024)
The preemptive administration of dexmedetomidine before pancreatic IR provides significant protection to kidney and liver tissues, as evidenced by the histopathological and biochemical parameters in this study. The findings underscored the potential therapeutic role of dexmedetomidine in mitigating the multiorgan damage associated with pancreatic surgeries.