Insufficient Radiofrequency Ablation Promotes Hepatocellular Carcinoma Metastasis Through N6-Methyladenosine mRNA Methylation-Dependent Mechanism.

Tianhong SuManling HuangJunbin LiaoShuibin LinPeng YuJianhua YangYuhong CaiShenghua ZhuLixia XuZhenwei PengSui PengShuling ChenMing Kuang

Published in: Hepatology (Baltimore, Md.) (2022)

The m6 A-YTHDF1-EGFR axis promotes HCC progression after IRFA, supporting the rationale for targeting m6 A machinery combined with EGFR inhibitors to suppress HCC metastasis after RFA.

Keyphrases

radiofrequency ablation
small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
dna methylation
clinical trial
genome wide
cancer therapy
drug delivery