Impact of Sonic Hedgehog-dependent sphenoid bone defect on craniofacial growth.

Hélène GuyodoAurélie RizzoFarah DiabFanny NourySvetlana MironovMarie de TayracVéronique DavidSylvie OdentChristèle DubourgValérie Dupé

Published in: Clinical and experimental dental research (2024)

Haploinsufficiency of Shh leads to isolated craniofacial skeletal hypoplasia in adult mouse. This finding highlights the importance of radiographic monitoring of the skull base in all individuals with SHH gene mutations.

Keyphrases

bone mineral density
soft tissue
childhood cancer
postmenopausal women