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MiR-31-5p regulates the neuroinflammatory response via TRAF6 in neuropathic pain.
Yuqi Liu
Lijuan Wang
Chengcheng Zhou
Yuan Yuan
Bin Fang
Kaimei Lu
Fangxia Xu
Lianhua Chen
Lina Huang
Published in:
Biology direct (2024)
All the results reveal that miR-31-5p could potentially alleviate pain in CCI mouse models by inhibiting the TRAF6 mediated neuroinflammatory response. MiR-31-5p upregulation is highlighted here as new target for CCI treatment.
Keyphrases
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neuropathic pain
spinal cord
spinal cord injury
signaling pathway
mouse model
cell proliferation
gene expression
single cell
long non coding rna
pain management