Predicted proteome association studies of breast, prostate, ovarian, and endometrial cancers implicate plasma protein regulation in cancer susceptibility.

Isabelle Gregga Paul David Peter Pharoah Simon A Gayther Ani W Manichaikul Hae Kyung Im Siddhartha P Kar Joellen M Schildkraut Heather E Wheeler

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)

PWAS and colocalization are promising methods to identify potential molecular mechanisms underlying complex traits.

Keyphrases

papillary thyroid
prostate cancer
squamous cell
childhood cancer
genome wide
protein protein
benign prostatic hyperplasia
endometrial cancer
case control
amino acid
lymph node metastasis
binding protein
squamous cell carcinoma
gene expression
small molecule