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Immune cells are increased in normal breast tissues of BRCA1/2 mutation carriers.

Joshua OgonyTanya L HoskinMelody Stallings-MannStacey WinhamRushin BrahmbhattMuhammad Asad ArshadNagarajan KannanAlvaro PeñaTeresa AllersAlyssa BrownMark E ShermanDaniel W VisscherKeith L KnutsonDerek C RadiskyAmylou C Dueck
Published in: Breast cancer research and treatment (2022)
These preliminary analyses show that normal/benign breast lobules of BRCA mutation carriers contain increased immune cells compared with normal donor breast tissues, and BBD tissues appear overall more similar to BRCA carriers.
Keyphrases
  • gene expression
  • breast cancer risk