Comparative effects of the antioxidant glutathione with metformin and Diane-35 on hormonal, metabolic, and inflammatory indicators in a DHEA-induced PCOS rat model.
Aslı CoşarPınar ÖzcanFatma Basak TanogluOlgu Enis TokGülçin ÖzkaraHikmet Tunç TimurÇağlar ÇetinDuygu NeccarPublished in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2024)
Glutathione plays anti-inflammatory and antioxidant roles, similar to metformin, by lowering serum IL-6, insulin, testosterone, CRP, and MDA levels; decreasing atretic/cystic follicle count; and improving antral follicle count and folliculogenesis in PCOS patients.
Keyphrases
- anti inflammatory
- polycystic ovary syndrome
- oxidative stress
- end stage renal disease
- ejection fraction
- type diabetes
- newly diagnosed
- diabetic rats
- peripheral blood
- prognostic factors
- peritoneal dialysis
- high glucose
- insulin resistance
- skeletal muscle
- drug induced
- adipose tissue
- replacement therapy
- glycemic control
- patient reported